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Skeletal dysplasias

Definitions

Sir Thomas Fairbank of Edinburgh, Scotland, pioneered the work on skeletal dysplasias in his 1951 book, An Atlas of General Affections of the Skeleton.

Dysplasia

comes from Latin roots dys and plasia, meaning "bad growth". Therefore, if a patient has bones that are funny-shaped in some way, they are probably dysplastic.
Dysplasia is caused by intrinsic bone abnormality.
It is the preferred term for dwarfism
is used when the developmental changes to the skeleton are generalised.
Dysostosis


is a deformity or maldevelopment of a single bone or body segment. OR a term used when there are underlying mesodermal or ectodermal abnormalities
Dystrophy:


alludes to deformities caused by metabolic or nutritional problems
Dwarfism:

:
is pathological diminution of stature.
Is broadly divided into proportionate (midget) or disproportionate (short limb or short trunk) varieties
The short limb group can be further subdivided according to the site of maximal shortening:
rhizomelic - in the proximal portion of the limb
mesonelic - in the middle portion
acromelic - in the distal portion
Dystrophy:


alludes to deformities caused by metabolic or nutritional problems
Dwarfism:

:
is pathological diminution of stature.
Is broadly divided into proportionate (midget) or disproportionate (short limb or short trunk) varieties
The short limb group can be further subdivided according to the site of maximal shortening:
rhizomelic - in the proximal portion of the limb
mesonelic - in the middle portion
acromelic - in the distal portion
Disproportionate



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